- Induction
- Goal: to remove bulk of tumor
- Methods: surgery, radiation/chemotherapy, bone marrow transplant
- Effects: often the most intensive phase; side effects of treatment are potentially life threatening
- Consolidation
- Goal: to eliminate any remaining malignant cells
- Methods: often chemotherapy/radiation therapy
- Effects: side effects will still be evident
- Maintenance
- Goal: to keep child disease free
- Method: chemotherapy (this phase may last for several years)
- Observation
- Goal: to monitor the child at intervals for evidence of recurrent disease and complications of treatment
- Method: treatment is complete; child may continue in this stage indefinitely
- Late effects of treatment
- Impaired growth and development, usually related to radiation of growth centers
- CNS damage resulting in intellectual, psychologic, or neurologic sequelae
- Impaired pubertal development including hormonal or reproductive problems
- Development of secondary malignancy
- Psychologic problems (poor self-esteem, depression, anxiety) related to living with a life-threatening disease and complex treatment regimen
Side Effects - From combined effects of treatment: nausea, vomiting, diarrhea, alopecia, anemia (low RBCs), increased susceptibility to infection (low WBCs), bleeding (low platelets), stomatitis, mucositis, pain, learning problems
- From radiation (findings differ according to site radiated): sleepiness, reddened skin
- From chemotherapy: drug toxicity specific to agents used
- Developmental: behavior problems, avoidance of school and friends, low self-esteem or self-image
Nursing Interventions - Help child cope with intrusive procedures.
- Provide information geared to developmental level and emotional readiness.
- Explain what is going to happen, why it is necessary, and how it will feel.
- Allow child to handle and manipulate equipment.
- Use needle play as indicated.
- Allow child some control in situations (e.g., positioning, selecting injection site).
- Support child and parents.
- Maintain frequent clinical conferences to keep all informed.
- Always tell the truth.
- Acknowledge feelings and encourage child/family to express them, assure them that feelings are normal.
- Provide contact with another parent or an organized support group such as Candlelighters.
- Try to keep daily life as normal as possible.
- Minimize side effects of treatment.
- Skin breakdown
- Keep clean and dry; wash with warm water, no soaps or creams.
- Do not wash off radiation markings.
- Avoid exposure to sunlight.
- Avoid all topical agents with alcohol (perfumes and powders).
- Do not use electric heating pads or hot water bottles.
- Bone marrow suppression
- Decreased RBCs
- allow child to determine activities.
- provide frequent rest periods.
- Decreased WBCs
- avoid crowds, isolate from children with known communicable disease.
- evaluate any potential site of infection.
- monitor temperature elevations.
- Decreased platelets
- make environment safe.
- select activities that are physically safe.
- avoid use of salicylates.
- Administer transfusions as ordered.
- Interpret peripheral blood counts to guide specific interventions and precautions.
- Nausea and vomiting
- Administer antiemetic at least half an hour before chemotherapy; repeat as necessary.
- Encourage relaxation techniques.
- Eat light meal prior to administration of therapy.
- Ensure adequate oral intake or administer IV fluids as necessary.
- Alopecia
- Reduce trauma of hair loss (especially in children over age 5 years).
- Buy wig before hair falls out.
- Discuss various head coverings with boys and girls.
- Avoid exposing head to sunlight.
- Discuss feelings.
- Stomatitis, mucositis (see Pediatric Oncology - Bone Marrow Transplant in Unit 5).
- Nutrition deficits
- Establish baseline prior to start of treatment.
- Measure height and weight regularly.
- Provide small, frequent meals.
- Consult dietitian as needed.
- Provide high-calorie, high-protein supplements.
- Developmental delays
- Discuss limit setting, discipline.
- Some behavior problems might be side effects of drug therapy.
- Facilitate return to school as soon as able.
- Realize changing needs of child.
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